IUPAC Name :

(E)-but-2-enedioic acid;8-chloro-11-[1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene]-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine.

CAS Number :   182349-12-8

Structural Formula :

Cadila Pharmaceuticals, RUPATADINE FUMARATE, API

Molecular Weight :   03  g/mol

Molecular Formula:   C30H30ClN3O4

Features of the API :

  • Rupatadine Fumarate is a dual antagonist of histamine H1 and platelet-activating factor receptors.
  • Manufactured in an USFDA, WHO GMP, ISO 9001, OHSAS 18001 approved site.
  • Available in standard pack size of 25 Kgs Net packed in HDPE Carbouys.

Mechanism of Action :

  • Rupatadine is a second generation, non-sedating, long-acting histamine antagonist with selective peripheral H1receptor antagonist activity. It further blocks the receptors of the platelet-activating factor (PAF) according to in vitro and in vivo studies.
  • Rupatadine possesses anti-allergic properties such as the inhibition of the degranulation of mast cells induced by immunological and non-immunological stimuli, and inhibition of the release of cytokines, particularly of the tumor necrosis factors (TNF) in human mast cells and monocytes.